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      產(chǎn)品中心您現(xiàn)在的位置：首頁(yè) > 產(chǎn)品展示 > 生化與分子 > 小分子化合物 > Ganglioside GT1b . trisodium salt (bovine brain)
      
      
      
        
      
          
      
            
      
              
      Ganglioside GT1b . trisodium salt (bovine brain)
      
              
      
                
      更新時(shí)間：2022-01-27
      
                
      簡(jiǎn)要描述：
      
                 
      Ganglioside GT1b . trisodium salt (bovine brain)， Prevents neurotoxicity of glutamate on neuronal cells.
      
                 
      型號(hào)：廠商性質(zhì)：代理商瀏覽量：843
      
              
      
              
            
      
            
      
                
      
            
            
      
            
      
          
       
          
      
          
      
            
      
              
              
      
                
      Ganglioside GT1b . trisodium salt (bovine brain)
      Product Details
      Alternative Name:GT1b . 3Na (bovine brain), Trisialoganglioside GT1b . 3Na (bovine brain)

      Sequence:[II3(Neu5Ac)2, IV3(Neu5Ac)GgOse4Cer] [[α-Neu5Ac-(2→3)]-β-Gal(1→3)-β-GalNAc-(1→4)-[α-Neu5Ac-(2→8)-α-Neu5Ac-(2→3)]-β-Gal-(1→4)-β-Glc-(1→1')-Cer]

      Formula:C95H162N5O47 . 3Na

      MW:2126.3 . 69.0 (calculated on sphingosine C18:1 and stearic acid)

      CAS:59247-13-1

      Purity:≥98% (TLC)

      Appearance:White solid.

      Solubility:Soluble in chloroform/methanol/DI water, 2:1:0.1; forms micellar solution in water.

      Shipping:Ambient

      Long Term Storage:-20°C

      Regulatory Status:RUO - Research Use Only

      ALX-302-011
      Please mouse over
      ALX-302-011

      Product Literature References
      GT1b-induced neurotoxicity is mediated by the Akt/GSK-3/tau signaling pathway but not caspase-3 in mesencephalic dopaminergic neurons: E.S. Chung, et al.; BMC Neurosci. 11, 74 (2010), Abstract;
      Gangliosides prevent glutamate and kainate neurotoxicity in primary neuronal cultures of neonatal rat cerebellum and cortex: M. Favaron, et al.; PNAS 85, 7351 (1988), Abstract;
      General Literature References
      Botulinum neurotoxin: a marvel of protein design: M. Montal; Annu. Rev. Biochem. 79, 591 (2010), Abstract; Full Text

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